About Targeted Medical Pharma Inc.
Corporate History
Targeted Medical Pharma Inc. was originally founded as Targeted Medical Foods in 1999 and became a Limited Liability Company in 2002. TMP began distributing proprietary Medical Food products in the United States in 2001.
The early development of the Company's products began in the cardiovascular testing laboratory. Certain patterns of autonomic nervous system derangement were observed on long-term electrocardiographic (EKG) recordings. These abnormal patterns corresponded to specific disease states and were associated with conditions known to have increased nutritional requirements specific to certain diseases. Over a period of five years, Company scientists assembled an extensive database of peer reviewed medical and scientific journal articles that confirmed that the common threads linking certain disease states were a variety of neurotransmitter deficiencies and imbalances. The challenge was then to identify the anatomical cause of neurotransmitter depletion and to develop interventions that would encourage the body to restore neurotransmitter levels that would ameliorate the symptoms of disease.read more»
In 1998, the Company scientists joined a group of investigators from the University of Texas, Southwestern Medical Center to attempt to determine the underlying causes of Gulf War Syndrome, a condition characterized by neurotransmitter depletion. After many years of testing and analysis, the results of this study revealed that lesions in key areas of the brain were associated with the disease process. This work was published in November 2004 in the American Journal of Medicine.
Sentra AM and Sentra PM® were the first products developed to address the needs of patients suffering from the effects of chemical exposures. Using the benchmark of Heart Rate Variability analysis to measure autonomic nervous system response to therapeutic interventions, the five-step process that became Targeted Cellular Technology® was developed.
In 2003, Physician Therapeutics was formed to distribute products to dispensing physicians and pharmacies in the United States. In December 2006, Laboratory Industry Services and Physician Therapeutics were absorbed into Targeted Medical Pharma Inc., A Delaware Corporation
On April 10, 2003 Targeted Medical Foods LLC entered into a Licensing Agreement for the Sales and Marketing Rights for six proprietary TCT medicinal nutrient products with J Network, Inc ("JNT"). The exclusive agreement was signed and provided for Targeted Medical Foods LLC, to manufacture and JNT to distribute on a mass distribution brands known as Lister V®, Sentra AM®, Sentra PM®, AppTrim®, and Nutra Smokeless, in Japan.
Targeted Medical Foods LLC entered into a Licensing Agreement for the Sales and Marketing Rights for five proprietary TCT medicinal nutrient products with Pliva Krakow Pharmaceutical Company ("Pliva"). The exclusive agreement was signed on August 7, 2003 and provided for the Company to manufacture and Pliva Krakow to distribute the products known as Sentra AM®, Sentra PM®, Nutra Smokeless, and AppTrim®, into fourteen (14) countries throughout the "Territory" of Eastern and Central Europe.
In 2006 the first six convenience packed products were developed featuring proprietary Medical Foods packaged for convenience with generic pharmaceuticals traditionally prescribed for specific disease states. The Company developed an additional 54 Convenience Packed Medical Foods with generic pharmaceuticals. The products include therapeutic systems for hypertension, pain syndromes, sleep disorders, metabolic syndrome, asthma, and viral infection.
In 2007, the company completed its first double-blind placebo-controlled trial of Medical Foods with co-administered generic pharmaceuticals. This study demonstrated the efficacy of medical foods administered alone to manage the increased nutrient requirements of a particular disease. Targeted Medical Pharma Inc. also completed development of its proprietary medical billing system that allowed point of care dispensing physicians to directly bill Insurance companies for medical foods, medical food co-packs and generic pharmaceuticals.
In 2008, The Company completed its development of the unique PDRx dispensing software system that facilitates dispensing, inventory control, billing and collections at the point of care.
Timeline for Double Blind Clinical Trials
Targeted Medical Pharma Inc. Development Timeline